My lab specialises in
cardiovascular haemodynamics. We investigate methods to assess cardiovascular function based on the
analysis of pulse wave signals, such as blood pressure, blood flow, and photoplethysmogram waves. These signals can be measured
in vivo using a variety of devices (including wearable sensors) and are influenced by the heart, the vasculature, and the respiratory and autonomic nervous systems.
We develop novel
models for simulating pulse wave signals under a variety of physiological and pathophysiological conditions. We develop
methods for calibrating these models and understanding physical mechanisms underlying their results. We also investigate
signal processing techniques to assess the functions of the cardiovascular, respiratory and autonomic nervous systems.
My group's research is described here.
An important computational tool for our research activities is the in-house code
Nektar1D, which I started developing during my PhD.
Nektar1D simulates blood pressure, blood flow and luminal area waves in arterial networks using the nonlinear, one-dimensional (1D) formulation of blood flow in compliant vessels.
Nektar1D has allowed us to show that
fast and accurate calculation of pulse wave signals in large arteries is feasible on a standard PC.
A complete list of my journal papers can be found below. For
Scopus click
here, for
Google Scholar here, and for
ResearchGate here.