Jordi Alastruey, PhD, CEng, FHEA
Group Leader
Digital Twins for Healthcare
School of Biomedical Engineering & Imaging Sciences
4th floor, North Wing
St Thomas' Hospital
SE1 7EH London
United Kingdom
Research
My lab specialises in cardiovascular haemodynamics. We investigate methods to assess cardiovascular function by analysing pulse wave signals, such as blood pressure and photoplethysmogram (PPG) waves. These signals, measured in vivo using devices including wearable sensors, are influenced by the heart, vasculature, and the respiratory and autonomic nervous systems.

We develop (i) models to simulate pulse wave signals under various physiological and pathophysiological conditions, (ii) methods to calibrate these models and understand the underlying mechanisms, and (iii) signal processing techniques to support clinical decision-making. My group's research is described here.

A key tool in our research is Nektar1D, an in-house code I began developing during my PhD. Nektar1D simulates blood pressure, flow, and luminal area waves in arterial networks using a nonlinear, one-dimensional (1D) model. It enables fast and accurate pulse wave calculations in large arteries on standard PCs.

For a full list of my publications, see below. My work is also available on Scopus, Google Scholar, and ResearchGate.
Main Academic Roles
08/2024 - now
Reader in Biomedical Engineering at King's College London, UK
School of Biomedical Engineering & Imaging Sciences
09/2017 - 07/2024
Senior Lecturer at King's College London, UK
School of Biomedical Engineering & Imaging Sciences
11/2013 - 08/2017
Lecturer at King's College London, UK
School of Biomedical Engineering & Imaging Sciences
08/2006 - 10/2013
British Heart Foundation (BHF) Research Fellow at Imperial College London (Department of Bioengineering) and King's College London (School of Biomedical Engineering & Imaging Sciences)
Experimental and numerical modelling of blood flow in the cardiovascular system to improve our understanding of hypertension
07/2006 - 10/2009
Postdoctoral Research Associate at Imperial College London, UK, Departments of Aeronautics and Bioengineering
Experimental and numerical modelling of blood flow in the cardiovascular system with applications to cerebral haemodynamics
External Positions
04/2024 - now
02/2024 - now
Scientific Board and General Assembly Member
Horizon project VIrtual Twins as tools for personalised clinicAL care (VITAL)
10/2023 - now
Working Group Co-Leader, Technological and Innovation
Association for Research into Arterial Structure and Physiology
07/2023 - now
Project Management Board Member
EURAMET European Partnership on Metrology project Uncertainty quantification for machine learning models applied to photoplethysmography signals (QUMPHY)
03/2023 - now
11/2019 - 05/2024
Working Group Leader, Physiological and Technical Background – from Bench to Bedside
COST Action Network for Research in Vascular Ageing
(My group was involved in the research activities described here.)
Education
02/2003 - 07/2006
PhD Thesis in Biomedical Engineering at Imperial College London, UK, Departments of Aeronautics and Bioengineering
1996 - 2002
BSc and MSc in Civil Engineering
Universitat Politècnica de Catalunya (UPC)
Publications