My research aimed to better understand blood flow hemodynamics in arteries, using numerical modeling. I particularly focused on coupled 1D-0D models, which produce efficient wave propagation results, while presenting a limited complexity and parametrisation.
My work aimed to develop innovative tools to help assess the efficiency of physiological indices and methods of wave analysis. I developed a
database of virtual healthy subjects and used it to assess the efficiency of a variety of foot-to-foot pulse wave velocities in estimating aortic stiffness.
I also participated in a challenging project on hypertension. Using numerical modeling together with experimental
in vitro studies, the project aimed at developing a diagnostic tool for hypertensive patients.
My PhD thesis focused on the particular application of bypass surgeries in lower-limb arteries. Using a 1D-0D numerical model parametrised with patient-specific
in vivo data, I improved the understanding of waves in pathological arteries and graft.
During my first post-doctorate, I studied the feasability of a new type of VAD for the particular Fontan heart pathology, using simple 0D models of the arterio-venous circulation and the heart and detailed local 3D models. Once optimised, we tested the new device on an
in vitro bench.