My research interests focus on using physiological measurements and numerical modelling to characterise cardiovascular haemodynamics, providing insights that may help explain and predict cardiovascular diseases.

My current work focuses on modelling cardiovascular haemodynamics as part of the VITAL (VIrtual Twins as tools for personalised clinicAL care) project. This involves generating disease-specific datasets of virtual subjects that will contribute to the digital human twins for individualised and sex-specific optimisation of pharmacological or interventional therapies for cardiovascular diseases, including hypertension, heart failure. I am also working on a project aimed at understanding the role of systo-diastolic coupling in heart failure with preserve ejection fraction (HFpEF). HFpEF is thought to be due to impaired relaxation and filling of the left ventricle, with contractile function and hence ejection fraction preserved. However, new data suggests that a major cause of HFpEF is inefficient early systolic contraction. I am using analytical tools to evaluate a new metric of early systolic function to help identify new treatments for this type of heart failure.